THE IMPACT OF HYPOXYTHERAPY (IN MOUNTAIN AIR) ON PHYSICAL REHABILITATION
DOI:
https://doi.org/10.32782/pub.health.2024.2.8Keywords:
hypoxia therapy, hypoxic training, rehabilitation, medical rehabilitation, physical rehabilitationAbstract
Topicality. Hypoxia therapy is one of the most effective methods of physical rehabilitation. Hypoxic training is used for various disorders of human physiological activity, and can also be used by the elderly and pregnant women. The aim of the study is to investigate the influence of various hypoxic conditions during physical rehabilitation, namely, how the conditions of high mountain air affect the process of physical rehabilitation. Materials and methods. A systematic thematic bibliographic review was used to conduct this review study. The main portal for searching for publications was the Scopus and Web of sciences databases. In addition, we searched the bibliography of each article to include more studies related to the topic. A total of 45 publications were analysed. The sources studied were classified according to their focus. The study included publications covering aspects related to the impact of hypoxytherapy (in mountain air) on physical rehabilitation. Results and discussion. The paper deals with the literature sources where the most effective methods of hypoxytherapy are collected and analysed. The results of the effectiveness of hypoxytherapy in comparison with traditional methods are also presented. Conclusion. It has been established that hypoxia therapy has a number of positive effects on the human body. It promotes activation of haematopoiesis and increases the number of red blood cells, which improves oxygen supply to tissues and organs. This is especially important in the process of recovery from injury or surgery. Hypoxia activates mechanisms that reduce inflammation. This helps speed up the healing and recovery process after various injuries or diseases, especially in muscles and joints. By adapting to the conditions of reduced oxygen concentration, patients increase their physical endurance, which is an important aspect of rehabilitation after injuries or surgery, especially for athletes. Hypoxia stimulates metabolism and stimulates the nervous system. Hypoxia therapy has a large number of different approaches for the prevention and physical rehabilitation of patients. According to the literature review, the most practical is the method of passive intermittent hypoxic training and intermittent hypoxic-hyperoxic training. They are several times more effective than other methods of treatment and improvement of the physical state of human health.
References
Storz J.F., Cheviron Z.A. Physiological genomics of adaptation to high-altitude hypoxia. Annual Review of Animal Biosciences, 2021. Vol. 9 (1). P. 149–171.
Durand F., Raberin A. Exercise-induced hypoxemia in endurance athletes: consequences for altitude exposure. Frontiers in Sports and Active Living. 2021. Vol. 3. 663674.
Soo J., Girard O., Ihsan M., Fairchild T. The use of the SpO2 to FiO2 ratio to individualize the hypoxic dose in sport science, exercise, and health settings. Frontiers in Physiology. 2020. Vol. 11. 570472.
Haryanto A.I., Kadir S., Suardika I. K., Muktiani N. R. Analysis of Maximal Volume of Oxygen for Gorontalo Contingent Martial Arts Athletes. ACTIVE: Journal of Physical Education, Sport, Health and Recreatio. 2024. Vol. 13 (2).
Yang L., Dai M., Cao Q., Ding S., Zhao Z., Cao X., ... Fu F. Real-time monitoring hypoxia at high altitudes using electrical bioimpedance technique: an animal experiment. Journal of Applied Physiology. 2021. Vol. 130 (4). P. 952–963.
Wang F., Zhang H., Xu T., Hu Y., Jiang Y. Acute exposure to simulated high-altitude hypoxia alters gut microbiota in mice. Archives of Microbiology. 2022. Vol. 204 (7). P. 412.
Storz J.F. High-altitude adaptation: mechanistic insights from integrated genomics and physiology. Molecular biology and evolution. 2021. Vol. 38 (7). P. 2677–2691.
Baloglu E., Nonnenmacher G., Seleninova A., Berg L., Velineni K., Ermis-Kaya E., Mairbäurl H. The role of hypoxiainduced modulation of alveolar epithelial Na+-transport in hypoxemia at high altitude. Pulmonary Circulation. 2020. Vol. 10 (1_suppl). P. 50–58.
Beall C.M., Strohl K.P. Adaptations to high-altitude hypoxia. In Oxford Research Encyclopedia of Anthropology. 2021.
Bagińska M., Kałuża A., Tota Ł., Piotrowska A., Maciejczyk M., Mucha D., ... Pałka T. The Impact of Intermittent Hypoxic Training on Aerobic Capacity and Biometric-Structural Indicators among Obese Women-A Pilot Study. Journal of Clinical Medicine. 2024. Vol. 13 (2). P. 380.
Ramchandani R., Florica I.T., Zhou Z., Alemi A., Baranchuk A. Review of Athletic Guidelines for High-Altitude Training and Acclimatization. High Altitude Medicine & Biology. 2024. Vol. 25 (2). P. 113–121.
Sharma P., Mohanty S., Ahmad Y. A study of survival strategies for improving acclimatization of lowlanders at highaltitude. Heliyon. 2023. Vol. 9 (4).
Woodbridge H.R., Norton C., Jones M., Brett S.J., Alexander C.M., Gordon A.C. Clinician and patient perspectives on the barriers and facilitators to physical rehabilitation in intensive care: a qualitative interview study. BMJ open. 2023. Vol. 13 (11). e073061.
Zlotnik S., Weiss P.L., Raban D.R., Houldin-Sade A. Use of gamification for adult physical rehabilitation in occupational therapy; a novel concept?. Hong Kong Journal of Occupational Therapy. 2023. Vol. 36 (2). P. 51–56.
Rahmati M., Shamsi M.M., Woo W., Koyanagi A., Lee S. W., Yon D. K., ... Smith L. Effects of physical rehabilitation interventions in COVID-19 patients following discharge from hospital: A systematic review. Journal of integrative medicine. 2023. Vol. 21 (2). P. 149–158.
Karloh M., Barbosa G.B., Matias T.S. The unifying theory of physical activity: a promising holistic perspective for physiotherapy and rehabilitation. Physiotherapy. 2023. Vol. 120. P. 36–37.
Walsh C.M., Gull K., Dooley D. Motor rehabilitation as a therapeutic tool for spinal cord injury: New perspectives in immunomodulation. Cytokine & growth factor reviews. 2023. Vol. 69. P. 80–89.
Li L., Han J., Li X., Guo B., Wang X. Customized Trajectory Optimization and Compliant Tracking Control for Passive Upper Limb Rehabilitation. Sensors. 2023. Vol. 23 (15). P. 6953.
Abu-Dakka F.J., Valera A., Escalera J.A., Abderrahim M., Page A., Mata V. Passive exercise adaptation for ankle rehabilitation based on learning control framework. Sensors. 2020. Vol. 20 (21). P. 6215.
Lee K.E., Choi M., Jeoung B. Effectiveness of rehabilitation exercise in improving physical function of stroke patients: a systematic review. International journal of environmental research and public health. 2022. Vol. 19 (19). P. 12739.
Gamonales J.M., Rojas-Valverde D., Vásquez J., Martínez-Guardado I., Azofeifa-Mora C., Sánchez-Ureña B., Ibáñez S.J. An update to a comprehensive assessment of the methods and effectiveness of resistance training in normobaric hypoxia for the development of strength and muscular hypertrophy. Applied Sciences. 2023. Vol. 13 (2). P. 1078.
de Carvalho C.D., Putti G.M., Foresti Y.F., Ribeiro F.A., Andreossi J.C., de Campos G.F., Papoti M. Recovery in normobaric hypoxia as an additional stimulus for high-intensity intermittent training. Science & Sports. 2023. Vol. 38 (2). P. 189–196.
Yu Q., Kong Z., Zou L., Chapman R., Shi Q., Nie J. Comparative efficacy of various hypoxic training paradigms on maximal oxygen consumption: A systematic review and network meta-analysis. Journal of Exercise Science & Fitness. 2023.
He Z., Qiang L., Liu Y., Gao W., Feng T., Li Y., ... Girard O. Effect of Hypoxia Conditioning on Body Composition in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis. Sports Medicine-Open. 2023. Vol. 9 (1). P. 89.
Liang Y., Ruan W., Jiang Y., Smalling R., Yuan X., Eltzschig H.K. Interplay of hypoxia-inducible factors and oxygen therapy in cardiovascular medicine. Nature Reviews Cardiology. 2023. Vol. 20 (11). P. 723–737.
Uzun A.B., Iliescu M.G., Stanciu L.E., Ionescu E.V., Ungur R.A., Ciortea V.M., ... Tofolean D.E. Effectiveness of intermittent hypoxia-hyperoxia therapy in different pathologies with possible metabolic implications. Metabolites. 2023. Vol. 13 (2). P. 181.
Scott B.R. Hypoxic training for strength enhancement. In Hypoxia Conditioning in Health, Exercise and Sport. 2024. Р. 233–246.
Merellano-Navarro E., Camacho-Cardenosa M., Costa G.P., Wiggers E., Marcolino Putti G., Evandro Nogueira J., ... Trapé Á.A. Effects of different protocols of moderate-intensity intermittent hypoxic training on mental health and quality of life in brazilian adults recovered from COVID-19: The AEROBICOVID double-blind randomized controlled study. In Healthcare. 2023. Vol. 11. № 23.Р. 3076. MDPI.
Hohenauer E., Freitag L., Costello J. T., Williams T. B., Küng T., Taube W., ... Clijsen R. The effects of normobaric and hypobaric hypoxia on cognitive performance and physiological responses: A crossover study. PLoS One. 2022. Vol. 17 (11). e0277364.
Falla M., Hüfner K., Falk M., Weiss E.M., Vögele A., Jan van Veelen M., ... Strapazzon G. Simulated acute hypobaric hypoxia effects on cognition in helicopter emergency medical service personnel-a randomized, controlled, single-blind, crossover trial. Human factors. 2024. Vol. 66 (2). Р. 404–423.
Lu Y., Zhou X., Cheng J., Ma Q. Early intensified rehabilitation training with hyperbaric oxygen therapy improves functional disorders and prognosis of patients with traumatic brain injury. Advances in Wound Care. 2021. Vol. 10 (12). P. 663–670.
Ma C., Xu H., Yan M., Huang J., Yan W., Lan K., ... Zhang Z. Longitudinal changes and recovery in heart rate variability of young healthy subjects when exposure to a hypobaric hypoxic environment. Frontiers in Physiology. 2022. Vol. 12. 688921.
Mallet R.T., Mayer K., Xi L. Intermittent hypoxia Effective systemic modality for cardiac rehabilitation. In Hypoxia Conditioning in Health, Exercise and Sport. 2024. Р. 155–165.
Muangritdech N., Hamlin M. J., Sawanyawisuth K., Prajumwongs P., Saengjan W., Wonnabussapawich P., ... Manimmanakorn A. Hypoxic training improves blood pressure, nitric oxide and hypoxia-inducible factor-1 alpha in hypertensive patients. European journal of applied physiology. 2010. Vol. 120. P. 1815–1826.
Norberto M.S., Torini J.V.G., Firmino M.S., Papoti M. Validation of Air Storage System for Hypoxia Exposure During Exercise. High Altitude Medicine & Biology. 2024.
Ghaleb A.M., Ramadan M.Z., Badwelan A., Mansour L., Al-Tamimi J., Aljaloud K.S. Determining the time needed for workers to acclimatize to hypoxia. International Journal of Biometeorology. 2020. Vol. 64. P. 1995–2005.
Peltonen J.E., Leppävuori A., Lehtonen E., Mikkonen R. S., Kettunen O., Nummela A., ... Linnamo V. Combined intermittent hypoxic exposure at rest and continuous hypoxic training can maintain elevated hemoglobin mass after a hypoxic camp. Journal of Applied Physiology. 2024. Vol. 137 (2). P. 409–420.
Behrendt T., Bielitzki R., Behrens M., Herold F., Schega L. Effects of intermittent hypoxia-hyperoxia on performanceand health-related outcomes in humans: A systematic review. Sports medicine-open. 2022. Vol. 8 (1). P. 70.
Camacho-Cardenosa A., Camacho-Cardenosa M., Martínez-Guardado I., Brazo-Sayavera J., Timon R., Olcina G. Effects of repeated-sprint training in hypoxia on physical performance of team sports players. Revista Brasileira de Medicina do Esporte. 2020. Vol. 26 (2). P. 153–157.
Tobin B., Costalat G., Renshaw G.M. Intermittent not continuous hypoxia provoked haematological adaptations in healthy seniors: hypoxic pattern may hold the key. European journal of applied physiology. 2020. Vol. 120 (3). P. 707–718.
Behrendt T., Bielitzki R., Behrens M., Herold F., Schega L. Effects of intermittent hypoxia-hyperoxia on performanceand health-related outcomes in humans: A systematic review. Sports medicine-open. 2022. Vol. 8 (1). P. 70.
Takei N., Kakinoki K., Girard O., Hatta H. Short-Term repeated wingate training in hypoxia and normoxia in sprinters. Frontiers in Sports and Active Living. 2020. Vol. 2. P. 43.
Faulhaber M., Schneider S., Rausch L.K., Dünnwald T., Menz V., Gatterer H., ... Schobersberger W. Repeated Short-Term Bouts of Hyperoxia Improve Aerobic Performance in Acute Hypoxia. The Journal of Strength & Conditioning Research. 2023. Vol. 37 (10). P. 2016–2022.
Behrendt T., Bielitzki R., Behrens M., Herold F., Schega L. Effects of intermittent hypoxia–hyperoxia on performanceand health-related outcomes in humans: A systematic review. Sports medicine-open. 2022. Vol. 8 (1). P. 70.
Hencz A.J., Magony A., Thomas C., Kovacs K., Szilagyi G., Pal J., Sik A. Short-term hyperoxia-induced functional and morphological changes in rat hippocampus. Frontiers in Cellular Neuroscience. 2024. Vol. 18. P. 1376577.